Participate in the PROMPT Study

Welcome to the PROMPT Study! PROMPT stands for PONV Rescue Outcomes after AMisulPride Treatment. PROMPT is a registry-based study that will collect and analyze real-world evidence on the presentation, evaluation, and rescue treatment of post-operative nausea and vomiting.

PROMPT is managed through the Perioperative and Anesthesia Care Explorer (PACE) Registry, and is powered by ArborMetrix.

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Surgical team

What Is the PROMPT Study?

The PROMPT Study is a multicenter matched cohort analysis that will compare patient outcomes before and after introduction of intravenous amisulpride as rescue treatment in the post-anesthesia care unit. It has several aims:

  • Identify practice patterns and trends in the treatment of PONV.
  • Characterize the effectiveness and adverse event profiles of key treatments used for PONV rescue.
  • Quantify the impact of PONV rescue treatment on important post-surgical outcome measures.

 

What Is the PACE Registry?

The Perioperative and Anesthesia Care Explorer (PACE) Registry is home to the PROMPT Study. Participating sites will use PACE to participate in the PROMPT Study and analyze and understand their own outcomes.

Data from the PROMPT Study will be collected from de-identified electronic health records into the PACE Registry. In the case of the PROMPT Study, the PACE Registry will:

  • Curate data elements relevant to perioperative medicine and the treatment of PONV.
  • Build a measurement strategy using advanced data science that quantifies outcome variability and identifies pathways to improved treatment.
  • Focus on answering high-priority questions utilizing data harvested from the PROMPT Study.

Prompt Study

Understand Treatment Patterns and Outcomes for
Post-Operative Nausea and Vomiting

Anesthesia patient

PONV Is a Common Complication

The PROMPT Study is filling the need for large, real-world observational studies in perioperative medicine. This study will help answer key questions as new treatments for PONV become available.

  • What are the practice patterns?
  • What treatments are being used?
  • What is the impact on key clinical metrics?

A Registry-Based Observational Study

The PROMPT Study will include academic and community hospitals and health systems across the United States. It will collect and analyze real-world data on the presentation, evaluation, and rescue treatment of PONV.

Participating sites and researchers will use the PACE Registry to investigate and publish key outcomes and trends to advance quality and safety.

Anesthesiologist
ECMO-devices-585x390

Valuable Insights for Hospitals

Sites that participate in the PROMPT Study will use the PACE Registry to analyze and understand their own outcomes. They will:

  • Gain insight into deidentified, retrospective data collection from tens of thousands of patient records.
  • Leverage research-grade evidence suitable for publication.
  • Access web-based reports on quality metrics, workflow, and throughput.

Ready to Dive Into the PROMPT Study?

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Data for the PROMPT Study will be collected from de-identified electronic health records into the PACE Registry, and compiled and analyzed by an independent data science company, ArborMetrix.

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